Interaction with the Yes-associated protein (YAP) allows TEAD1 to positively regulate NAIP expression

Polyoma Small T Antigen Interacts with YES-Associated Protein (YAP) to Regulate Cell

Authors' Affiliations: 1 Department of Developmental, Molecular and Chemical Biology 8 Tufts University School of Medicine; Sackler School of Graduate Biomedical Sciences, Tufts 9 University; Department of Cancer Biology, Dana-Farber Cancer Institute; Department of 10 Biological Chemistry and Molecular Pharmacology; , 6 Department of Biochemistry, University 11 of Kashmir, Kashmir, India; 7 Dep...

Expression of Yes-associated protein (YAP) in breast phyllodes tumor.

This study aimed to identify expression profiles of Yes-associated protein (YAP) and its phosphorylated form (pYAP) in phyllodes tumor (PT) of human breast and verify the clinical implications. We selected PTs from the pathologic archive and reviewed the histologic features (141 benign, 27 borderline, and 15 malignant). We made tissue microarray (TMA) block from the formalin-fixed paraffin-embe...

Expression of Yes-associated protein (YAP) in metastatic breast cancer.

The purpose of this study was to investigate the expression of Yes-associated protein (YAP) in different metastatic sites in metastatic breast cancer and to determine the clinical implications of these patterns. Immunohistochemical staining was used to investigate the expression of YAP and phospho-YAP in tissue microarrays from 122 cases of metastatic breast cancer (bone metastasis = 29, brain ...

Dual roles of yes-associated protein (YAP) in colorectal cancer

Yes-associated protein (YAP) is a downstream effector molecule of a newly emerging tumour suppressor pathway called the Hippo pathway. YAP is a transcriptional co-activator and mis-expressed in various cancers, including colorectal cancer (CRC). Accumulating studies show that the high expression of nuclear YAP is linked with tumour progression and decreased survival. Nuclear YAP can interact wi...

Yes-associated protein (YAP) and Transcriptional co-activator with PDZ-binding motif (TAZ;